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TIM 3 Rabbit pAb

Cat No.: APA3381
Size:
Product Name: TIM 3 Rabbit pAb
Cat No.: APA3381
source: Rabbit
reactivity: Human
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:100
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human TIM 3
calculated molecular weight: 33 kDa
observed molecular weight: 45-70 kDa
genbank accession number: Q8TDQ0
gene id (ncbi): 84868
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: TIM3; CD366; KIM-3; TIMD3; Tim-3; TIMD-3; HAVcr-2
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]