PAI1 Rabbit pAb
Cat No.: APA3375
Size:
Product Name: | PAI1 Rabbit pAb |
Cat No.: | APA3375 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human PAI1 |
calculated molecular weight: | 45 kDa |
observed molecular weight: | 45 kDa |
genbank accession number: | P05121 |
gene id (ncbi): | 5054 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | PAI; PAI1; PAI-1; PLANH1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |