TrkA Rabbit pAb
Cat No.: APA3366
Size:
Product Name: | TrkA Rabbit pAb |
Cat No.: | APA3366 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human TrkA |
calculated molecular weight: | 88 kDa |
observed molecular weight: | 140 kDa |
genbank accession number: | P04629 |
gene id (ncbi): | 4914 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008] |