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BACE1 Rabbit pAb

Cat No.: APA3334
Size:
Product Name: BACE1 Rabbit pAb
Cat No.: APA3334
source: Rabbit
reactivity: Mouse, Rat
applications: WB,IHC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse BACE1
calculated molecular weight: 56 kDa
observed molecular weight: 70 kDa
genbank accession number: P56818
gene id (ncbi): 23821
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ASP2; Bace; C76936
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques, which accumulate in the brains of human Alzheimer--s disease patients. Homozygous knockout mice for this gene exhibit a wide range of nervous system defects, growth retardation, metabolic abnormalities, and increased neonatal lethality. [provided by RefSeq, Nov 2015]