CIRBP Rabbit pAb
Cat No.: APA3333
Size:
Product Name: | CIRBP Rabbit pAb |
Cat No.: | APA3333 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:200 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human CIRBP |
calculated molecular weight: | 19 kDa |
observed molecular weight: | 19 kDa |
genbank accession number: | Q14011 |
gene id (ncbi): | 1153 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CIRP |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3---untranslated regions (3---UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed. |