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CIRBP Rabbit pAb

Cat No.: APA3333
Size:
Product Name: CIRBP Rabbit pAb
Cat No.: APA3333
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:200
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human CIRBP
calculated molecular weight: 19 kDa
observed molecular weight: 19 kDa
genbank accession number: Q14011
gene id (ncbi): 1153
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CIRP
category: Primary Ab
concentration: 0.5mg/ml
background: Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3---untranslated regions (3---UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.