CREB3 Rabbit pAb
Cat No.: APA3330
Size:
Product Name: | CREB3 Rabbit pAb |
Cat No.: | APA3330 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CREB3 |
calculated molecular weight: | 41 kDa |
observed molecular weight: | 41 kDa |
genbank accession number: | O43889 |
gene id (ncbi): | 10488 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | LZIP; LUMAN; sLZIP |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009] |