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Met Rabbit pAb

Cat No.: APA3325
Size:
Product Name: Met Rabbit pAb
Cat No.: APA3325
source: Rabbit
reactivity: Mouse
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse Met
calculated molecular weight: 154 kDa
observed molecular weight: 145-170 kDa
genbank accession number: P16056
gene id (ncbi): 17295
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HGF; HGFR; Par4; c-Met; AI838057
category: Primary Ab
concentration: 0.5mg/ml
background: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1.