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Caspase-3 p12 Rabbit pAb

Cat No.: APA3307
Size:
Product Name: Caspase-3 p12 Rabbit pAb
Cat No.: APA3307
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:500
ICC/IF: 1:20
FC: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Caspase-3 p12
calculated molecular weight: 32 kDa
observed molecular weight: 32,12 kDa
genbank accession number: P42574
gene id (ncbi): 836
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CPP32; SCA-1; CPP32B
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer--s disease. [provided by RefSeq, Aug 2017]