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SIGIRR Rabbit pAb

Cat No.: APA3298
Size:
Product Name: SIGIRR Rabbit pAb
Cat No.: APA3298
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human SIGIRR
calculated molecular weight: 46 kDa
observed molecular weight: 46 kDa
genbank accession number: Q6IA17
gene id (ncbi): 59307
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: TIR8; IL-1R8
category: Primary Ab
concentration: 0.5mg/ml
background: Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.