SIGIRR Rabbit pAb
Cat No.: APA3298
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| Product Name: | SIGIRR Rabbit pAb |
| Cat No.: | APA3298 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000-1:5000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human SIGIRR |
| calculated molecular weight: | 46 kDa |
| observed molecular weight: | 46 kDa |
| genbank accession number: | Q6IA17 |
| gene id (ncbi): | 59307 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | TIR8; IL-1R8 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP. |