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Proteasome subunit alpha type 6 Rabbit pAb

Cat No.: APA3274
Size:
Product Name: Proteasome subunit alpha type 6 Rabbit pAb
Cat No.: APA3274
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
ICC/IF: 1:50
FC: 1:20-1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Proteasome subunit alpha type 6
calculated molecular weight: 27 kDa
observed molecular weight: 27 kDa
genbank accession number: P60900
gene id (ncbi): 5687
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IOTA; p27K; PROS27
category: Primary Ab
concentration: 0.5mg/ml
background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]