Adiponectin Rabbit pAb
Cat No.: APA3267
Size：
| Product Name: | Adiponectin Rabbit pAb |
| Cat No.: | APA3267 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:200 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Adiponectin |
| calculated molecular weight: | 26 kDa |
| observed molecular weight: | 30 kDa |
| genbank accession number: | Q60994 |
| gene id (ncbi): | 11450 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Ad; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |