• Drop us a line for any questions: info@assayvector.com

xCT Rabbit pAb

Cat No.: APA3260
Size:
Product Name: xCT Rabbit pAb
Cat No.: APA3260
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human xCT
calculated molecular weight: 55 kDa
observed molecular weight: 55 kDa
genbank accession number: Q9UPY5
gene id (ncbi): 23657
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: xCT; CCBR1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011]