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Lipocalin-2/NGAL Rabbit pAb

Cat No.: APA3255
Size:
Product Name: Lipocalin-2/NGAL Rabbit pAb
Cat No.: APA3255
source: Rabbit
reactivity: Mouse, Rat
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse Lipocalin-2/NGAL
calculated molecular weight: 23 kDa
observed molecular weight: 23 kDa
genbank accession number: P11672
gene id (ncbi): 16819
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: NRL; 24p3; Sip24; AW212229
category: Primary Ab
concentration: 0.5mg/ml
background: Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration.