Lipocalin-2/NGAL Rabbit pAb
Cat No.: APA3255
Size:
Product Name: | Lipocalin-2/NGAL Rabbit pAb |
Cat No.: | APA3255 |
source: | Rabbit |
reactivity: | Mouse, Rat |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse Lipocalin-2/NGAL |
calculated molecular weight: | 23 kDa |
observed molecular weight: | 23 kDa |
genbank accession number: | P11672 |
gene id (ncbi): | 16819 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | NRL; 24p3; Sip24; AW212229 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. |