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fetal hemoglobin Rabbit pAb

Cat No.: APA3229
Size:
Product Name: fetal hemoglobin Rabbit pAb
Cat No.: APA3229
source: Rabbit
reactivity: Human
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human fetal hemoglobin
calculated molecular weight: 16 kDa
observed molecular weight: 16 kDa
genbank accession number: P69905+P68871
gene id (ncbi): 3039+3043
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HBGA; HBGR; HBG-T2; HSGGL1; PRO2979
category: Primary Ab
concentration: 0.5mg/ml
background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5---epsilon -- gamma-G -- gamma-A -- delta -- beta--3--. [provided by RefSeq, Jul 2008]