MMP9 Rabbit pAb
Cat No.: APA3212
Size:
Product Name: | MMP9 Rabbit pAb |
Cat No.: | APA3212 |
source: | Rabbit |
reactivity: | Human, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 IHC: 1:50 ICC/IF: 1:100 FC: 1:200 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human MMP9 |
calculated molecular weight: | 78 kDa |
observed molecular weight: | 78 kDa |
genbank accession number: | P14780 |
gene id (ncbi): | 4318 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | GELB; CLG4B; MMP-9; MANDP2 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP--s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008] |