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PDCD6 Rabbit pAb

Cat No.: APA3211
Size:
Product Name: PDCD6 Rabbit pAb
Cat No.: APA3211
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PDCD6
calculated molecular weight: 22 kDa
observed molecular weight: 22 kDa
genbank accession number: O75340
gene id (ncbi): 10016
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ALG2; ALG-2; PEF1B
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]