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WAVE 1 Rabbit pAb

Cat No.: APA3208
Size:
Product Name: WAVE 1 Rabbit pAb
Cat No.: APA3208
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
FC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human WAVE 1
calculated molecular weight: 62 kDa
observed molecular weight: 90 kDa
genbank accession number: Q92558
gene id (ncbi): 8936
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: WAVE; SCAR1; WAVE1
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]