WAVE 1 Rabbit pAb
Cat No.: APA3208
Size:
Product Name: | WAVE 1 Rabbit pAb |
Cat No.: | APA3208 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000-1:5000 FC: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human WAVE 1 |
calculated molecular weight: | 62 kDa |
observed molecular weight: | 90 kDa |
genbank accession number: | Q92558 |
gene id (ncbi): | 8936 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | WAVE; SCAR1; WAVE1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |