IL1 Receptor I Rabbit pAb
Cat No.: APA3201
Size：
| Product Name: | IL1 Receptor I Rabbit pAb |
| Cat No.: | APA3201 |
| source: | Rabbit |
| reactivity: | Mouse |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse IL1 Receptor I |
| calculated molecular weight: | 67 kDa |
| observed molecular weight: | 67,80 kDa |
| genbank accession number: | P13504 |
| gene id (ncbi): | 16177 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | IL-iR; CD121a; CD121b; IL-1R1; Il1r-1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity). |