CHD3 Rabbit pAb
Cat No.: APA3188
Size:
Product Name: | CHD3 Rabbit pAb |
Cat No.: | APA3188 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CHD3 |
calculated molecular weight: | 227 kDa |
observed molecular weight: | 260 kDa |
genbank accession number: | Q12873 |
gene id (ncbi): | 1107 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ZFH; Mi-2a; Mi2-ALPHA |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |