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TLE 1 Rabbit pAb

Cat No.: APA3171
Size:
Product Name: TLE 1 Rabbit pAb
Cat No.: APA3171
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human TLE 1
calculated molecular weight: 83 kDa
observed molecular weight: 83 kDa
genbank accession number: Q04724
gene id (ncbi): 7088
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ESG; ESG1; GRG1
category: Primary Ab
concentration: 0.5mg/ml
background: Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.