Cathepsin B Rabbit pAb
Cat No.: APA3163
Size：
| Product Name: | Cathepsin B Rabbit pAb |
| Cat No.: | APA3163 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:50 FC: 1:100 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Cathepsin B |
| calculated molecular weight: | 37 kDa |
| observed molecular weight: | 44,27,24 kDa |
| genbank accession number: | P10605 |
| gene id (ncbi): | 13030 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CB |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the peptidase C1 family and preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to generate the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. Homozygous knockout mice for this gene exhibit reduced pancreatic damage following induced pancreatitis and reduced hepatocyte apoptosis in a model of liver injury. Pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Aug 2015] |