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PDGFR beta Rabbit pAb

Cat No.: APA3162
Size:
Product Name: PDGFR beta Rabbit pAb
Cat No.: APA3162
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human PDGFR beta
calculated molecular weight: 124 kDa
observed molecular weight: 190 kDa
genbank accession number: P09619
gene id (ncbi): 5159
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Aug 2017]