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SIRT1 Rabbit pAb

Cat No.: APA3150
Size:
Product Name: SIRT1 Rabbit pAb
Cat No.: APA3150
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100
ICC/IF: 1:20
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human SIRT1
calculated molecular weight: 82 kDa
observed molecular weight: 120 kDa
genbank accession number: Q923E4
gene id (ncbi): 23411
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: SIR2; SIR2L1; SIR2alpha
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]