ETAA1 Rabbit pAb
Cat No.: APA3137
Size:
Product Name: | ETAA1 Rabbit pAb |
Cat No.: | APA3137 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human ETAA1 |
calculated molecular weight: | 103 kDa |
observed molecular weight: | 103 kDa |
genbank accession number: | Q9NY74 |
gene id (ncbi): | 54465 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ETAA16 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717). Probably only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717). |