Histone H2A Rabbit pAb
Cat No.: APA3117
Size：
| Product Name: | Histone H2A Rabbit pAb |
| Cat No.: | APA3117 |
| source: | Rabbit |
| reactivity: | Saccharomyces cerevisiae |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of Histone H2A |
| calculated molecular weight: | 14 kDa |
| observed molecular weight: | 14 kDa |
| genbank accession number: | P04912 |
| gene id (ncbi): | |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | H2A2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |