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Histone H2A Rabbit pAb

Cat No.: APA3117
Size:
Product Name: Histone H2A Rabbit pAb
Cat No.: APA3117
source: Rabbit
reactivity: Saccharomyces cerevisiae
applications: WB
clonality: Polyclonal
recommended dilution: WB: 1:1000
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of Histone H2A
calculated molecular weight: 14 kDa
observed molecular weight: 14 kDa
genbank accession number: P04912
gene id (ncbi):
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: H2A2
category: Primary Ab
concentration: 0.5mg/ml
background: Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.