Growth Hormone Rabbit pAb
Cat No.: APA3105
Size:
Product Name: | Growth Hormone Rabbit pAb |
Cat No.: | APA3105 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human Growth Hormone |
calculated molecular weight: | 25 kDa |
observed molecular weight: | 22 kDa |
genbank accession number: | P01241 |
gene id (ncbi): | 2688 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | GH; GHN; GH-N; GHB5; hGH-N; IGHD1B |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature. [provided by RefSeq, Jul 2008] |