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C3 Rabbit pAb

Cat No.: APA3103
Size:
Product Name: C3 Rabbit pAb
Cat No.: APA3103
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:200
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human C3
calculated molecular weight: 187 kDa
observed molecular weight: 187 kDa
genbank accession number: P01024
gene id (ncbi): 718
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p
category: Primary Ab
concentration: 0.5mg/ml
background: Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. [provided by RefSeq, Nov 2015]