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CARD9 Rabbit pAb

Cat No.: APA3099
Size:
Product Name: CARD9 Rabbit pAb
Cat No.: APA3099
source: Rabbit
reactivity: Human
applications: WB,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human CARD9
calculated molecular weight: 62 kDa
observed molecular weight: 62 kDa
genbank accession number: Q9H257
gene id (ncbi): 64170
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CANDF2; hCARD9
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a member of the CARD protein family, which is defined by the presence of a characteristic caspase-associated recruitment domain (CARD). CARD is a protein interaction domain known to participate in activation or suppression of CARD containing members of the caspase family, and thus plays an important regulatory role in cell apoptosis. This protein was identified by its selective association with the CARD domain of BCL10, a postive regulator of apoptosis and NF-kappaB activation, and is thought to function as a molecular scaffold for the assembly of a BCL10 signaling complex that activates NF-kappaB. Several alternatively spliced transcript variants have been observed, but their full-length nature is not clearly defined. [provided by RefSeq, Jul 2008]