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SEPT7 Rabbit pAb

Cat No.: APA3090
Size:
Product Name: SEPT7 Rabbit pAb
Cat No.: APA3090
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human SEPT7
calculated molecular weight: 51 kDa
observed molecular weight: 51 kDa
genbank accession number: Q16181
gene id (ncbi): 989
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CDC3; CDC10; SEPT7A; NBLA02942
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]