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YB1 Rabbit pAb

Cat No.: APA3089
Size:
Product Name: YB1 Rabbit pAb
Cat No.: APA3089
source: Rabbit
reactivity: Human
applications: WB,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000-1:5000
FC: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human YB1
calculated molecular weight: 36 kDa
observed molecular weight: 49 kDa
genbank accession number: P67809
gene id (ncbi): 4904
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: YB1; BP-8; CSDB; DBPB; YB-1; CBF-A; CSDA2; EFI-A; NSEP1; NSEP-1; MDR-NF1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a highly conserved cold shock domain protein that has broad nucleic acid binding properties. The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation, pre-mRNA splicing, DNA reparation and mRNA packaging. This protein is also a component of messenger ribonucleoprotein (mRNP) complexes and may have a role in microRNA processing. This protein can be secreted through non-classical pathways and functions as an extracellular mitogen. Aberrant expression of the gene is associated with cancer proliferation in numerous tissues. This gene may be a prognostic marker for poor outcome and drug resistance in certain cancers. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Sep 2015]