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GAPDH Rabbit pAb

Cat No.: APA3068
Size:
Product Name: GAPDH Rabbit pAb
Cat No.: APA3068
source: Rabbit
reactivity: Human, Mouse, Rat, Monkey, Chicken, Dog
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:100
ICC/IF: 1:50
FC: 1:50
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human GAPDH
calculated molecular weight: 36 kDa
observed molecular weight: 36 kDa
genbank accession number: P04406
gene id (ncbi): 2597
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: G3PD; GAPD; HEL-S-162eP
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]