SP17 Rabbit pAb
Cat No.: APA3066
Size:
Product Name: | SP17 Rabbit pAb |
Cat No.: | APA3066 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:50 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human SP17 |
calculated molecular weight: | 17 kDa |
observed molecular weight: | 17 kDa |
genbank accession number: | Q15506 |
gene id (ncbi): | 53340 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CT22; SP17; SP17-1 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009] |