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Mast Cell Chymase Rabbit pAb

Cat No.: APA3048
Size:
Product Name: Mast Cell Chymase Rabbit pAb
Cat No.: APA3048
source: Rabbit
reactivity: Human
applications: WB,IHC
clonality: Polyclonal
recommended dilution: WB: 1:2000-1:10000
IHC: 1:100
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Mast Cell Chymase
calculated molecular weight: 27 kDa
observed molecular weight: 27 kDa
genbank accession number: P23946
gene id (ncbi): 1215
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CYH; MCT1; chymase
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants. [provided by RefSeq, Apr 2015]