Plasminogen Rabbit pAb
Cat No.: APA3046
Size:
Product Name: | Plasminogen Rabbit pAb |
Cat No.: | APA3046 |
source: | Rabbit |
reactivity: | Mouse |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse Plasminogen |
calculated molecular weight: | 91 kDa |
observed molecular weight: | 100 kDa |
genbank accession number: | P20918 |
gene id (ncbi): | 18815 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | Pg; AI649309 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells (By similarity). |