eIF4E Rabbit pAb
Cat No.: APA3041
Size：
| Product Name: | eIF4E Rabbit pAb |
| Cat No.: | APA3041 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:5000 IHC: 1:20 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human eIF4E |
| calculated molecular weight: | 25 kDa |
| observed molecular weight: | 25 kDa |
| genbank accession number: | P06730 |
| gene id (ncbi): | 1977 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5-- end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5---cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |