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Cytochrome P450 3A5 Rabbit pAb

Cat No.: APA3035
Size:
Product Name: Cytochrome P450 3A5 Rabbit pAb
Cat No.: APA3035
source: Rabbit
reactivity: Human
applications: WB,IHC,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Cytochrome P450 3A5
calculated molecular weight: 57 kDa
observed molecular weight: 57 kDa
genbank accession number: P20815
gene id (ncbi): 1577
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CP35; PCN3; CYPIIIA5; P450PCN3
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]