Anterior Gradient 2 Rabbit pAb
Cat No.: APA3026
Size:
Product Name: | Anterior Gradient 2 Rabbit pAb |
Cat No.: | APA3026 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:100 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human Anterior Gradient 2 |
calculated molecular weight: | 20 kDa |
observed molecular weight: | 18 kDa |
genbank accession number: | O95994 |
gene id (ncbi): | 10551 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | AG2; AG-2; HPC8; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] |