Lin28A Rabbit pAb
Cat No.: APA3012
Size：
| Product Name: | Lin28A Rabbit pAb |
| Cat No.: | APA3012 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Lin28A |
| calculated molecular weight: | 23 kDa |
| observed molecular weight: | 23 kDa |
| genbank accession number: | Q9H9Z2 |
| gene id (ncbi): | 79727 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015] |