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Apolipoprotein A I Rabbit pAb

Cat No.: APA3011
Size:
Product Name: Apolipoprotein A I Rabbit pAb
Cat No.: APA3011
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:5000
IHC: 1:20
ICC/IF: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Apolipoprotein A I
calculated molecular weight: 31 kDa
observed molecular weight: 31 kDa
genbank accession number: P02647
gene id (ncbi): 335
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: apo(a)
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015]