Apolipoprotein A I Rabbit pAb
Cat No.: APA3011
Size:
Product Name: | Apolipoprotein A I Rabbit pAb |
Cat No.: | APA3011 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,IHC,ICC/IF,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:5000 IHC: 1:20 ICC/IF: 1:50 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Apolipoprotein A I |
calculated molecular weight: | 31 kDa |
observed molecular weight: | 31 kDa |
genbank accession number: | P02647 |
gene id (ncbi): | 335 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | apo(a) |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The encoded preproprotein is proteolytically processed to generate the mature protein, which promotes cholesterol efflux from tissues to the liver for excretion, and is a cofactor for lecithin cholesterolacyltransferase (LCAT), an enzyme responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein. [provided by RefSeq, Dec 2015] |