alpha 1b Adrenergic Receptor Rabbit pAb
Cat No.: APA3010
Size:
Product Name: | alpha 1b Adrenergic Receptor Rabbit pAb |
Cat No.: | APA3010 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20-1:100 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human alpha 1b Adrenergic Receptor |
calculated molecular weight: | 57 kDa |
observed molecular weight: | 57 kDa |
genbank accession number: | P35368 |
gene id (ncbi): | 147 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | ADRA1; ALPHA1BAR |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008] |