PDE3A Rabbit pAb
Cat No.: APA3005
Size:
Product Name: | PDE3A Rabbit pAb |
Cat No.: | APA3005 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of human PDE3A |
calculated molecular weight: | 125 kDa |
observed molecular weight: | 125 kDa |
genbank accession number: | Q14432 |
gene id (ncbi): | 5139 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | HTNB; CGI-PDE; CGI-PDE A; CGI-PDE-A |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] |