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ATF2 Rabbit pAb

Cat No.: APA3003
Size:
Product Name: ATF2 Rabbit pAb
Cat No.: APA3003
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000
IHC: 1:20
ICC/IF: 1:50
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human ATF2
calculated molecular weight: 55 kDa
observed molecular weight: 70 kDa
genbank accession number: P15336
gene id (ncbi): 1386
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: HB16; CREB2; TREB7; CREB-2; CRE-BP1
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell--s DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014]