ATF2 Rabbit pAb
Cat No.: APA3003
Size：
| Product Name: | ATF2 Rabbit pAb |
| Cat No.: | APA3003 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IHC,ICC/IF,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:2000 IHC: 1:20 ICC/IF: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human ATF2 |
| calculated molecular weight: | 55 kDa |
| observed molecular weight: | 70 kDa |
| genbank accession number: | P15336 |
| gene id (ncbi): | 1386 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | HB16; CREB2; TREB7; CREB-2; CRE-BP1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell--s DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene [provided by RefSeq, Jan 2014] |