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Gli3 Rabbit pAb

Cat No.: APA3002
Size:
Product Name: Gli3 Rabbit pAb
Cat No.: APA3002
source: Rabbit
reactivity: Human
applications: WB,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human Gli3
calculated molecular weight: 170 kDa
observed molecular weight: 200 kDa
genbank accession number: Q5IS56
gene id (ncbi): 2737
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190
category: Primary Ab
concentration: 0.5mg/ml
background: This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq, Jul 2008]