CAD Rabbit pAb
Cat No.: APA2994
Size:
Product Name: | CAD Rabbit pAb |
Cat No.: | APA2994 |
source: | Rabbit |
reactivity: | Human |
applications: | WB,ICC/IF,FC,IP |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 IP: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human CAD |
calculated molecular weight: | 243 kDa |
observed molecular weight: | 243 kDa |
genbank accession number: | P27708 |
gene id (ncbi): | 790 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | CDG1Z; GATD4; EIEE50 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |