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CD22 Rabbit pAb

Cat No.: APA2985
Size:
Product Name: CD22 Rabbit pAb
Cat No.: APA2985
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF,IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:20
IP: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human CD22
calculated molecular weight: 95 kDa
observed molecular weight: 140 kDa
genbank accession number: P20273
gene id (ncbi): 933
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: SIGLEC2; SIGLEC-2
category: Primary Ab
concentration: 0.5mg/ml
background: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling.