S100A9 Rabbit pAb
Cat No.: APA2984
Size:
Product Name: | S100A9 Rabbit pAb |
Cat No.: | APA2984 |
source: | Rabbit |
reactivity: | Mouse, Rat |
applications: | WB,IHC,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 IHC: 1:100 ICC/IF: 1:200 FC: 1:100 |
format: | Liquid |
isotype: | IgG |
immunogen: | Recombinant protein of mouse S100A9 |
calculated molecular weight: | 13 kDa |
observed molecular weight: | 13 kDa |
genbank accession number: | P31725 |
gene id (ncbi): | 20202 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | p14; Cagb; GAGB; L1Ag; BEE22; MRP14; 60B8Ag; AW546964 |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. |