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S100A9 Rabbit pAb

Cat No.: APA2984
Size:
Product Name: S100A9 Rabbit pAb
Cat No.: APA2984
source: Rabbit
reactivity: Mouse, Rat
applications: WB,IHC,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100
ICC/IF: 1:200
FC: 1:100
format: Liquid
isotype: IgG
immunogen: Recombinant protein of mouse S100A9
calculated molecular weight: 13 kDa
observed molecular weight: 13 kDa
genbank accession number: P31725
gene id (ncbi): 20202
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: p14; Cagb; GAGB; L1Ag; BEE22; MRP14; 60B8Ag; AW546964
category: Primary Ab
concentration: 0.5mg/ml
background: S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions.