Prostaglandin D Synthase Rabbit pAb
Cat No.: APA2983
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| Product Name: | Prostaglandin D Synthase Rabbit pAb |
| Cat No.: | APA2983 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Prostaglandin D Synthase |
| calculated molecular weight: | 21 kDa |
| observed molecular weight: | 26 kDa |
| genbank accession number: | P41222 |
| gene id (ncbi): | 5730 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008] |