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CaMKII Rabbit pAb

Cat No.: APA2979
Size:
Product Name: CaMKII Rabbit pAb
Cat No.: APA2979
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:100
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human CaMKII
calculated molecular weight: 54 kDa
observed molecular weight: 54 kDa
genbank accession number: Q13554
gene id (ncbi): 815
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: CAMKA
category: Primary Ab
concentration: 0.5mg/ml
background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]