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Delta Opioid Receptor Rabbit pAb

Cat No.: APA2968
Size:
Product Name: Delta Opioid Receptor Rabbit pAb
Cat No.: APA2968
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,ICC/IF,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
ICC/IF: 1:100
FC: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human Delta Opioid Receptor
calculated molecular weight: 40 kDa
observed molecular weight: 40 kDa
genbank accession number: P41143
gene id (ncbi): 4985
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: OPRD
category: Primary Ab
concentration: 0.5mg/ml
background: G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.