Delta Opioid Receptor Rabbit pAb
Cat No.: APA2968
Size:
Product Name: | Delta Opioid Receptor Rabbit pAb |
Cat No.: | APA2968 |
source: | Rabbit |
reactivity: | Human, Mouse, Rat |
applications: | WB,ICC/IF,FC |
clonality: | Polyclonal |
recommended dilution: | WB: 1:1000 ICC/IF: 1:100 FC: 1:20 |
format: | Liquid |
isotype: | IgG |
immunogen: | A synthetic peptide of human Delta Opioid Receptor |
calculated molecular weight: | 40 kDa |
observed molecular weight: | 40 kDa |
genbank accession number: | P41143 |
gene id (ncbi): | 4985 |
purification method: | Affinity Purification |
conjugate: | Un-conjugated |
storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
synonyms: | OPRD |
category: | Primary Ab |
concentration: | 0.5mg/ml |
background: | G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine. |