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DPD Rabbit pAb

Cat No.: APA2960
Size:
Product Name: DPD Rabbit pAb
Cat No.: APA2960
source: Rabbit
reactivity: Human
applications: WB,IHC,ICC/IF
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of human DPD
calculated molecular weight: 111 kDa
observed molecular weight: 111 kDa
genbank accession number: Q12882
gene id (ncbi): 1806
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: DHP; DPD; DHPDHASE
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]